Skeletal muscle LINE-1 ORF1 mRNA is higher in older humans, but decreases with endurance exercise and is negatively associated with higher physical activity

Paul A. Roberson,Matthew A. Romero,Shelby C. Osburn,Petey W. Mumford,Christopher G. Vann,Carlton D. Fox,Danielle J. McCullough,Michael D. Brown,Michael D. Roberts

Skeletal muscle LINE-1 ORF1 mRNA is higher in older humans, but decreases with endurance exercise and is negatively associated with higher physical activity

2019

Paul A. Roberson
Matthew A. Romero
Shelby C. Osburn
Petey W. Mumford
Christopher G. Vann
Carlton D. Fox
Danielle J. McCullough
Michael D. Brown
Michael D. Roberts

The Long Interspersed Nuclear Element-1 (L1) is a retrotransposon which constitutes 17% of the human genome and is associated with various diseases and aging. Estimates suggest ~100 L1 copies are c...

Keywords:

Diabetes mellitus
Anesthesia
Human genome
Chemistry
Endocrinology
Retrotransposon
Methylation
Endurance training
Internal medicine
Messenger RNA
Skeletal muscle
Gene
Genome

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