Antioxidant enzymes and lipid peroxidation in C57Bl/6 and BALB/c mice

Superoxide dismutase and catalase activities and levels of thiobarbituric acid-reactive lipid peroxidation (LPO) products were estimated in the liver of C57B1/6 and BALB/c mice. The results indicate that although antioxidant enzymes are more active in BALB/c mice, compensation of oxidation processes in this strain is possible only if LPO-inducing agents are absent or present at low levels, and that these agents, including exogenous ones, may be expected to activate lipid oxidation in this strain to a greater extent than in C57Bl/6 mice.