Isolation and structural clarification of triterpenes from Cyclocarya paliurus: Cyclocaric acid A and B

Two triterpenes were isolated using bioassay guided fractionation from the ethanol extract of Cyclocarya paliurus. Comparison to NMR spectra from a prior isolation reported in literature showed these two compounds to be previously reported Cyclocaric Acids A and B. However, after additional research into the oleanolic class of compounds, an independent synthesis of the reported Cyclocaric Acid A from hederagenin was completed. The conclusion is that the previously reported structures were incorrect. Updated structure and NMR spectral data will be presented.