Development and validation of a digital Gleason score biomarker signature for risk stratification of patients with prostate cancer.

40 Background: Gleason score (GS) is the most widely used grading system of cell differentiation in prostate cancer and one of the best pathological predictors of disease progression. Patients with high GS (> 7) are the most likely to experience metastasis, whereas patients with low GS ( 7, using a Bonferroni adjusted T-Test with a p-value threshold of 0...