The Anti-ulcer Effect of Tibet Medicine of Gentiana macrophylla

ObjectiveTo study the anti-ulceration effect of Gentiana macrophylla from Tibet,and the mechanism of action.MethodsWe studied the effect of the Gentiana macrophylla ethanol extract on aspirin and absolute ethylalcohol-induced rat gastric ulcer models.ResultsThe results showed that the Gentiana macrophylla ethanol extract could significantly dwindle the areas of the gastric ulcer models.It could reduce the total quantity of gastric juice and the secrte of gastric protein if the quantity of Gentiana macrophylla ethanol extract were enough.There was no difference between them and control.ConclusionThe Gentiana macrophylla ethanol extract could prevent gastric ulcer and the mechanism need further research.