Microwave-assisted synthesis of 2,5-disubstituted pyrimidine derivatives via Buchwald-Hartwig amination
2019
Abstract Various 2,5-disubstituted pyrimidine derivatives were synthesized under microwave irradiation via Buchwald-Hartwig amination. This concise approach provides interesting scaffolds in good to high yields and with large functional group compatibility. These novel chemical entities could be used as building blocks in drug design.
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