Enhanced production of styrene by engineered Escherichia coli and in situ product recovery (ISPR) with an organic solvent

Background Styrene is a large-volume commodity petrochemical, which has been used in a wide range of polymer industry as the main building block for the construction of various functional polymers. Despite many efforts to produce styrene in microbial hosts, the production titers are still low and are not enough to meet the commercial production of styrene.