Going Low in a World Going High: The Physiologic Use of Lower Frequency Electron Paramagnetic Resonance

Yakov Sergeevich Lebedev was a pioneer in high-frequency EPR, taking advantage of the separation of g-factor anisotropy effects from nuclear hyperfine splitting and the higher-frequency molecular motion sensitivity from higher-frequency measurements (Appl Magn Reson 7: 339–362, 1994). This article celebrates a second EPR subfield in which Prof. Lebedev pioneered, EPR imaging (Chem Phys Lett 99: 301–304, 1983). We celebrate the clinical enhancements that are suggested in this low-frequency work and imaging application to animal physiology at lower-than-standard EPR frequencies.