B7-H3 inhibits the IFN-γ-dependent cytotoxicity of Vγ9Vδ2 T cells against colon cancer cells

Huimin Lu,Tongguo Shi,Mingyuan Wang,Xiaomi Li,Yanzheng Gu,Xueguang Zhang,Guangbo Zhang,Weichang Chen

B7-H3 inhibits the IFN-γ-dependent cytotoxicity of Vγ9Vδ2 T cells against colon cancer cells

2020

Huimin Lu
Tongguo Shi
Mingyuan Wang
Xiaomi Li
Yanzheng Gu
Xueguang Zhang
Guangbo Zhang
Weichang Chen

The immunoregulatory protein B7-H3, a member of the B7 family, has been confirmed to be highly expressed in colon cancer. However, the exact influence of B7-H3 on the features and antitumor ability...

Keywords:

Cytotoxicity
Cancer research
Medicine
Colorectal cancer
γδt cells

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