488 Adjuvant radiotherapy in stage I ovarian cancer

The retrospective analysis of 141 patients with stage I ovarian cancer registered in the Institute of Oncology in Gliwice from January 1985 to December 1991 was undertaken. Subsequent to the surgery 91 patients were treated by external magavoltage irradiation and 50 had no further treatment. There was no significant difference between the groups with the respect to stage and histological grade distribution. In radiotherapy group 13% developed recurrent disease comparing to 12% in control group. Adjuvant radiotherapy had no benefit in terms of relapse rate and survival. Multivariate analysis showed that dose of irradiation and the irradiated volume did not influence the prognosis. Histological grade followed by stage were the major predictors for relapse and significantly correlated with survival.