Study on the SFE condition for curcumin in Curcuma longa

Objective: To optimize the conditions of s upercritical fluid extraction(SFE) for curcumin in Curcuma longa. Method: Optimum extraction conditions were studied by orthogona l tests. The extracts were analyzed by HPLC. Result: Th e optimal extraction conditions were pressure 25 MPa, temperature 55 ℃, sta tic time 4 h, dynamic time 5 h, flow rate of CO 2 3.5 L·min -1 , c o-solvent ethanol 30%(mL·g -1 ). Conclusion: It is feasible to extract curcumin by SFE.[