A Novel Method of Preparing (S)‐5‐Fluoro‐3‐phenyl‐2‐ [1‐(9H‐purin‐6‐ylamino)propyl]‐3H‐quinazolin‐4‐one.

Idelalisib ((S)-5-fluoro-3-phenyl-2-[1-(9H-purin-6-ylamino)-propyl]-3H-quinazolin -4-one, 9) is the first-in-class, highly selective inhibitor of phosphoinositide 3-kinase p110δ; it has been clinic...