Preparation and In-vitro Release Performance of Sodium-iron Chlorophyllin Microcapsules

Abstract Objective To investigate the preparation and the drug in vitro release mechanism of Sodium-iron Chlorophyllin microcapsules. Methods Sodium-iron Chlorophyllin/ Ethylcellulose (EC) microcapsules were prepared by solvent- nonsolvent method. Model-fitting were used to study the in-vitro release mechanism of Sodium-iron Chlorophyllin microcapsules. Results The method has such advantages as simple technology, uniformity in diameters and drug loading. Conclusion The preparation procedure is simple. And the release mechanism of water-insoluble matrix preparations was fitting model.