Guillain-Barré syndrome seen in users of isotretinoin

We report Guillain-Barre syndrome in people taking oral isotretinoin, a retinoid drug used in secondary care for severe acne.1 The Committee on Safety of Medicines has received one other report of Guillain-Barre syndrome after oral isotretinoin (Committee on Safety of Medicines, private communication). Case 1 —A 31 year old man took 80 mg of oral isotretinoin a day for five weeks, during which he had epistaxis, dry lips, …