Trisomy 21-Associated Aggressive Periodontitis: A Five-Year Follow-Up

Introduction: This report explores the effective treatment of aggressive periodontitis in a 23-year-old male with Trisomy 21.Case Presentation: A 23-year-old male with Trisomy 21 presented with his mother with the chief complaint of “bleeding gums and bad breath.” Periodontal evaluation along with anaerobic microbiological culture was performed. Systemic antibiotics were given after the completion of the initial mechanical scaling and root planing (SRP). After reevaluation, the patient was placed on a 2-month recall in which antimicrobial therapy in the form of diluted sodium hypochlorite (1:40) and povidone-iodine (10%) was delivered subgingivally in addition to SRP. The patient remained on a 1- to 2-month recall.A reduction of mean probing depths, from 4.2 ±1.3 mm at baseline to 2.98 ± 0.89 mm, at 5 years (P <0.05) was observed. Percentage of sites with bleeding on probing showed a reduction from 100% at baseline to 16.66% at 5 years (P <0.05). The number of sites with probing depths measuring ≥6 mm was...