Historical Evaluation of the Film Badge Dosimetry Program at the Y-12 Facility in Oak Ridge, Tennessee Part 2 - Neutron Radiation

The disclosure relates to cycloalkylene azoles of general Formula I (I) wherein is a carbocyclic or carbopolycyclic group optionally carrying at least on a alkyl substituent, X is a grouping an oxygen or sulfur atom, and Y and Z, independently of each other, are or a nitrogen atom, as well as their pharmaceutically compatible addition salts with acids as well as processes for production thereof. The compounds possess strongly aromatase-inhibiting activity and are suitable for the preparation of medicinal agents. Methods for treating estrogen induced or stimulated tumors, male infertility, and impending cardiac infarction with these compounds are also provided as well as methods for inhibiting female fertility.