C60 Fullerenes Suppress Reactive Oxygen Species Toxicity Damage in Boar Sperm

Carboxylated C60 may be considered a novel antioxidant agent to be used as a semen extender supplement for assisted reproductive technology. Carboxylated C60 could enhance the motility parameters and characteristics of boar spermatozoa during liquid storage at 4 °C and protect boar sperm from oxidative stress by inhibiting the reactive-oxygen-species–induced protein dephosphorylation. Novel insights into the molecular mechanisms contributing to the protective effects of carboxylated C60 are provided.