Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

V. Stalin Raj,Huihui Mou,Saskia L. Smits,Dick H. W. Dekkers,Marcel A. Müller,Ronald Dijkman,Doreen Muth,Jeroen Demmers,Ali Moh Zaki,Ron A. M. Fouchier,Volker Thiel,Christian Drosten,Peter J. M. Rottier,Albert D.M.E. Osterhaus,Berend Jan Bosch,Bart L. Haagmans

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

2013

V. Stalin Raj
Huihui Mou
Saskia L. Smits
Dick H. W. Dekkers
Marcel A. Müller
Ronald Dijkman
Doreen Muth
Jeroen Demmers
Ali Moh Zaki
Ron A. M. Fouchier
Volker Thiel
Christian Drosten
Peter J. M. Rottier
Albert D.M.E. Osterhaus
Berend Jan Bosch
Bart L. Haagmans

Human coronavirus-EMC (hCoV-EMC) is a new coronavirus that has killed around half of the few humans infected so far; this study now identifies DPP4 as the receptor that this virus uses to infect cells.

Keywords:

Virus
Middle East respiratory syndrome coronavirus
Dipeptidyl peptidase-4
Coronavirus
Betacoronavirus
Middle East respiratory syndrome
Viral pathogenesis
Virology
Receptor
Biology
Pathogenesis
Lower respiratory tract infection
Respiratory disease

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