Isolation and Structures of New Azaphilone Derivatives, Falconensins E-G, from Emericella falconensis and Absolute Configurations of Falconensins A-G.

Three new azaphilone derivatives designated falconensins E (5), F (6), and G (7) were isolated from the mycelium of Emericella falconensis, along with falconensins A (1), B (2), C (3), D (4), and H (8), and three hopane-type triterpenes, zeorin (9), hopane-7β,22-diol (10), and hopane-6α,7β,22-triol (11). The structures of 5-7 were confirmed by spectroscopic investigation and chemical correlations. The absolute stereochemistry of falconensins A (1) to G (7) was also established.