Pharmacokinetics and in vivo stability of intraperitoneally administered therapeutic antibody catumaxomab

Peter Ruf,Michael Jäger,C. Volovat,Alexander Burges,Markus M. Heiss,Pauline Wimberger,B. Brandt,Horst Lindhofer

Pharmacokinetics and in vivo stability of intraperitoneally administered therapeutic antibody catumaxomab

2008

Peter Ruf
Michael Jäger
C. Volovat
Alexander Burges
Markus M. Heiss
Pauline Wimberger
B. Brandt
Horst Lindhofer

14006 Background: The EpCAM-specific trifunctional rat/mouse hybrid antibody catumaxomab simultaneously activates T cells and Fcγ-receptor positive immune cells redirecting them against the tumor. ...

Keywords:

Antibody
In vivo
Catumaxomab
Pharmacology
Medicine
Pharmacokinetics
Immune system
therapeutic antibody
Hybrid antibody

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