Особенности морфологии иммунного воспаления у пациентов с длительным течением посттравматического увеита

Purpose : to study the morphology of immune inflammation in patients with long-term posttraumatic uveitis. Material and methods . 54 patients who had one of their eyes removed after trauma and/or the results of surgical intervention were examined, followed by morphological examination of the removed eyes. The eyes were divided into three groups based on the type of trauma. Group I consisted of 20 eyes removed in the outcome of contusion injury. Group II was formed from 16 eyes removed as the outcome of a penetrating wound. Group III included 18 removed eyes after penetrating surgical interventions performed for retinal detachment and/or antiglaucomatous operations. Results . Morphological signs of immune inflammation were found in at least half of the cases in each of the studied groups. In group I (patients with concussion injury outcome) the incidence was the highest and amounted to 65 %, whilst in group II and III the signs were revealed in 56.3 %, and 50 %, respectively. In group III, all cases with immune post-traumatic inflammation referred to patients who underwent vitreoretinal interventions with the introduction of silicone oil into the vitreal cavity. Conclusions . According to comprehensive clinical and morphological study of 54 enucleated eyes, morphopathogenesis of immune inflammation with characteristic lymphoid infiltration and formation of lymphoid nodules was revealed in 57.4 % of cases. In patients with morphologically detected immune uveitis in history, exacerbation of post-traumatic inflammatory process was found to be related to acute respiratory viral diseases in 45.1 % of cases, which cannot exclude a possible role of the infectious factor in the development of an inflammatory reaction with signs of immune-based uveitis.