Distinct features of SARS-CoV-2-specific IgA response in COVID-19 patients

Hai-Qiong Yu,Baoqing Sun,Zhang Fu-fang,Jin-Cun Zhao,Xiaoyu Liu,Yi Min Li,Xizhuo Sun,Hong-Feng Liang,Bei Zhong,Zhifeng Huang,Peiyan Zheng,Lifeng Tian,Hui-Qi Qu,Dechen Liu,Eryi Wang,Xiaojun Xiao,Shiyue Li,Feng Ye,Li Guan,Dongsheng Hu,Hakon Hakonarson,Zhigang Liu,Nanshan Zhong

Distinct features of SARS-CoV-2-specific IgA response in COVID-19 patients

2020

Humoral immune response to SARS-CoV-2 showed an early response of IgA, instead of IgM, in COVID-19 patients. As highlighted by our study, enhanced IgA responses observed in severe COVID-19 might confer damaging effects in severe COVID-19.

Keywords:

Coronavirus disease 2019
Immunology
Diabetes mellitus
severe acute respiratory syndrome coronavirus 2
Immune system
Medicine
Physical therapy
2019 20 coronavirus outbreak

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