Copper(II)-Catalyzed Synthesis of Pyrimidines from Propargylic Alcohols and Amidine: A Propargylation—Cyclization—Oxidation Tandem Reaction.

Min Lin,Qing-zhen Chen,Yu Zhu,Xin-liang Chen,Ji-jun Cai,Ying-ming Pan,Zhuang-Ping Zhan

Copper(II)-Catalyzed Synthesis of Pyrimidines from Propargylic Alcohols and Amidine: A Propargylation—Cyclization—Oxidation Tandem Reaction.

2011

Min Lin
Qing-zhen Chen
Yu Zhu
Xin-liang Chen
Ji-jun Cai
Ying-ming Pan
Zhuang-Ping Zhan

The reaction offers a novel approach towards the synthesis of 2,4-disubstituted and 2,4,6-trisubstituted title compounds from aromatic propargyl alcohols.

Keywords:

Copper
Propargyl
Cascade reaction
Amidine
Organic chemistry
Catalysis
Chemistry

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