The observation of hypoxic-ischemic encephalopathy in the neonates with color Doppler energy image

Objective To study the cerebral blood flow changes of neonates with hypoxic-ischemic encephalopathy(HIE).Methods The arteriosum fete of upper border of medial surface of the cerebral hemisphere(ARUMS)and the blood flow parameters of cerebral arteries(CA)in 34 neonates with HIE and 25 health neonates were observed and compared by color Doppler energy image(CDE).Results The cerebral perfusion of neonates with HIE were decreased within 24 h after birth.the blood flow diameters of arteriolae of ARUMS were redUCed,and the ARUMS were few and scattered,even it were hardly showed;The velocity of CA wasdecreased and resistance index(RI)WaS significantly rised compared with health neonates(P<0.01). Afterwards,except for 2 severe cases,who were in continuous hypoperfusion and died,in the others,the cerebral perfusion started to be increased,the blood flow diameters of arteriolae of ARUMS were dilated,the ARUMS WaS recovered gradually,the velocity of CA WaS increased,and R1 waS decreased.From 24 to 96 h,9 cases in the moderate and severe groups show"luxury perfusion damage":the condition and the ultrasonographic in brain edema sign of these cases became more severe.and the blood flow diameters of arteriolae of ARUMS and all of velocity parameters were also increased over normal(P<0.05).But this phenomenon WaS not observed in other cas.Conclusions The monitoring ARUMS and blood flow parameters of CA of HIE by CDE is important in judging the"hypoperfusion damage".But it had to combine clinical manifestation with brain ultrasonography to judge whether the"luxury perfusion damage"exists. Key words: Uhrasonography,Doppler,color; Infant,Newborn; Cerebral ischemia; Cerebral anoxia