Micheliolide derivative and preparation method and use thereof

The invention relates to a micheliolide derivative shown as the formula (I) and a preparation method and use thereof, and in particular relates to a compound shown as the formula (I), and a pharmaceutical composition containing a therapeutically effective amount of the compound shown as the formula (I) and a pharmaceutically acceptable carrier or a pharmaceutical composition containing the therapeutically effective amount of the compound shown as the formula (I) and other anticancer drug, a preparation method of the micheliolide derivative, and use of the micheliolide derivative in preparation of drugs for treatment of cancer.