Acetaldehyde dehydrogenase 2 deficiency increases mitochondrial ROS emission and induces mitochondrial protease Omi/HtrA2 in skeletal muscle

Acetaldehyde dehydrogenase 2 (ALDH2) is an enzyme involved in redox homeostasis, as well as the detoxification process in alcohol metabolism. Nearly 8% of the world's population have an inactivatin...