Very Fine and Ultrafine Metals and Ischemic Heart Disease in the California Central Valley 1: 2003–2007

The enhancement of mortality associated with cardiovascular and specifically ischemic heart disease (IHD) has been observed in the southern California Central Valley since at least 1990, and it continues to be a major source of mortality. While there is a strong statistical association of IHD with wintertime PM2.5 mass, the causal agents are uncertain. Medical studies identify some potential causal agents, such as very fine and ultrafine metals, but they have not been fully characterized in most Central Valley regions. To provide improved information on specific and potentially causal agents, a five site aerosol sampling transect was conducted from Redding to Bakersfield during a 17-day period of strong stagnation, January 5–22, 2009. Mass and elemental components were measured every 3 h in eight particle size modes, ranging from 10 to 0.09 μm, while the ultrafine particles (<0.09 μm) were collected on Teflon filters. Ancillary studies were performed including direct upwind–downwind profiles across a heav...