Nosocomial pathogens and drug-resistance in an infectious disease hospital.

OBJECTIVE To study the nosocomial pathogens and drug-sensitivity in an infectious disease hospital.METHODS Retrospective analysis was conducted on sputum cultivation from patients who were hospitalized from Nov 2005 to Nov 2008 in the 302 hospital of PLA.RESULTS A total of 1832 pathogenic strains were isolated,most of which were Gram-negeative,of which Escherichia coliaccounted for 31.8%.Their multiple durg-resistance to anti-microbial agents was serious;Klebsiella pneumoniaeaccounted for 12.3%.Among Gram-positive bacilli,most of which were Staphylococcus epidermidisand S.aureus,accounted for 4.9% and 4.0%,espectively;among fungi,most of which were Candida albicans,accounted for 9.9%.CONCLUSIONS E.coliis the main nosocomial pathogen in an infectious disease hospital,and shows multiple durg-resistance to antimicrobial agents in drug sensitive test.