Contrast studies on the accommodation amplitude after different aspheric intraocular lenses implantation

Objective To compare the accommodation amplitude after different aspheric monofocal posterior chamber intraocular lenses (IOLs) implantation.Methods A prospective clinical study comprised 102 eyes of 102 patients who underwent phacoemulsification and intraocular lens implantation in Tianjin Medical University Eye Hospital from August 2010 to August 2011.Patients were divided into 3 groups according to the type of IOLs that implanted:Group Rayner were implanted with Rayner Superflex 920H IOL (Rayner); Group SN60WF were implanted with Acrysof IQ SN60WF IOL (Alcon); Group SN60AT were implanted with Acrysof NATURAL SN60AT IOL (Alcon).At 6 months postoperatively,uncorrected visual acuity,best corrected visual acuity,distance corrected near visual acuity were evaluated.Spherical aberration was measured by Hartmann-Shack wavefront sensor.Patients' subjective amplitude of accommodation was measured by integrated refractometer adjustment feet; while the objective amplitude of accommodation was measured by WR-5100 automatic computer Refractometer (GrandSeiko).Statistical analysis of count data and measurement data were done separately by the chi-square test and variance analysis.Pearson correlation was performed to analyze the association between parameters.Results The subjective amplitude of accommodation in the 3 groups were 2.00±0.58 D,2.26±0.60 D,2.29±0.48 D,respectively,while the objective amplitude of accommodation in the three groups were 0.87±0.37 D,1.01 ±0.38 D,1.04±0.37 D,respectively.There was no statistically significant difference between the subjective and objective amplitude of accommodation in the 3 groups (Fsub=2.662,Psub=0.075 ; Fob=1.925,Pob=0.151).When the pupil diameter was 3 mm,the spherical aberrations of the three groups were 0.08±0.04 μm,0.05±0.04 μm,0.14±0.05 μm,respectively.The difference of spherical aberration among the three groups was statistically significant (F=45.780,P＜0.01).No correlation was found in the spherical aberration with subjective or objective amplitude of accommodation (rsub=0.056,Psub=0.576;rob=0.095,Poh=0.343).Conclusion Compared with the implantation of Acrysof SN60AT spherical intraocular lens,the implantation of the Acrysof SN60WF aspheric intraocular lens and Rayner Superflex 920H aspheric intraocular lens do not affect the amplitude of accommodation significantly.No correlation is found between spherical aberration and subjective or objective amplitude of accommodation. Key words: Intraocular lens,aspheric; Amplitude of accommodation; Spherical aberration; Cataract