Effect of Lectins on Uptake of Polyamines

: The aliphatic polyamines (putrescine, cadaverine, spermidine, and spermine) are flexible polycations, since under physiological conditions they exhibit 2, 3, or 4 positive charges, respectively, and are able to rotate around the carbon-carbon or carbon-nitrogen bonds, imparting conformational flexibility (see Fig. 1). Fig. 1. The structure of the most common polyamines.