The effect of Lidocaine & Prilocaine on blood pressure, pulse rate and anxiety to undergo periodontal surgery

Abstract Background and Aim: The awareness of alterations of blood pressure, pluse rate and anxiety of patients during periodontal surgeries, not only prevents the occurrence of many emergencies, but also is effective in controlling patient during dental treatments. The present study was aimed to assess the effects of Lidocaine and Prilocaine on hemodynamic changes and anxiety. Materials & Methods: In this experimental clinical trial 80 patients attending periodontal department of Shahid Beheshti dental school (2005-2006) were divided by randomized sampling into two groups of Lidocaine and Prilocaine. Blood pressure, pulse rate and anxiety were analysed before and 10 minutes after injection of anaesthetic solution.The data was processed by means of SPSS software which included Chi-square,one and two way sampling Kolmogrov-Smirnov, Manwhitney and ANCOVA tests. Results: Local anesthesia had no significant effect on systolic blood pressure after injection, but Prilocaine with Felypressin increased more diastolic blood pressure than Lidocaine with Adrenaline. On the other hand, after injection, Lidocaine with Adrenaline increased heart rate than Prilocaine with Felypressin. There was no significant effect on anxiety after injection in both groups. Conclusion : The choice of local anesthesia influenced the heart rate and diastolic blood pressure in patients under periodontal surgery.