116 Autologous and Heterologous Neutralizing Antibody Responses in HIV-1 Infection

We have been studying the magnitude, breadth, kinetics and epitope specificity of the neutralizing antibody (nAb) response in early and chronic HIV-1 infection. The earliest nAb response was highly specific for the early autologous virus but within 1–2 years of infection, low titers of broadly neutr