ABCB1 and BMI1 mRNA expression in patients with chronic myeloid leukemia: impact on imatinib efficacy

Ahmed M. L. Bedewy,Shereen M. EL-Maghraby,Noha S. Kandil

ABCB1 and BMI1 mRNA expression in patients with chronic myeloid leukemia: impact on imatinib efficacy

2019

Ahmed M. L. Bedewy
Shereen M. EL-Maghraby
Noha S. Kandil

Background ATP-binding cassette transporters are important in the mechanism of multidrug resistance. ABCB1 displays a high affinity for imatinib. BMI1 is a polycomb group protein thought to be overexpressed in leukemic cells.

Keywords:

Cancer research
BMI1
Myeloid leukemia
Medicine
Imatinib
Messenger RNA
Real-time polymerase chain reaction
mrna expression
Multiple drug resistance
Reverse transcriptase
in patient

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations