Which regimen of antenatal corticosteroids is better to improve lung maturity, single or multiple courses? its a valid question today

RESUMEN Se hace una revision de la administracion antenatalde esteroides para acelerar la maduracionpulmonar fetal, su origen, bases fisiologicas y uti-lizacion en la practica clinica a traves del tiempohaciendo enfasis en el examen de los posibles be-neficios y riesgos de la administracion de cursosrepetidos. Al sopesar la evidencia e incertidum-bre alrededor de los riesgos de los cursos repeti-dos, no se recomienda su uso de rutina en la prac-tica clinica.Palabras clave: dexametasona, betametasona,parto prematuro. SUMMARY An overview about the evolution of antenatalsteroids administration in order to accelerate thelung maturity was done; it includes some topics aboutits origin, physiologic principles and use along thetime. The main objective was to review theevidence of possible beneficial and harmful effectsafter multiple courses. Provided that concernexists, and some evidence about the possible risksof weekly courses, they should not be prescribedroutinely for women at risk of preterm delivery.Key Words: corticosteroids, respiratorydistress syndrome, premature labour,