HighCTG repeatnumberinnodular thyroid tissue froma myotonic dystrophy patient

CTG triplet expansion was studiedin lymphocytes andthyroid tissue inapatient withmyotonicdystrophy (DM)andassociated thyroid nodulardisease. An approximately 7foldlarger amplification was foundinabnormalthyroid tissue comparedtolymphocytes, suggesting thatanomaliesintheputative DM kinasegene mightcontribute tothyroid dysfunction.