Effect of immunotherapy on selected immunologic indices in children with pollinosis

The study was carried out on 15 children with pollinosis. The children were treated with "Pollinex-Bencard" before the pollen season. We looked for changes of serum IgE levels and percentages of T (CD3) cells and their subsets CD4, CD8. After immunotherapy we observed a significant decrease of CD3, CD4 and CD8 cells, whereas no statistical difference was observed in the CD4/CD8 ratio. Three months after immunotherapy, serum IgE levels were significantly elevated, while after 9 months, markedly decreased.