Risk of de novo infection following acute kidney injury: A retrospective cohort study

Abstract Purpose Recent studies suggest that acute kidney injury (AKI) can affect distant organ function and increase non-renal complications. We determined whether AKI is associated with an increased risk of incident infections. Material and methods We conducted a one-year single-center retrospective cohort study, excluding patients readmitted to the ICU or for Results Of the 1001 included patients, infections were more frequent in those with AKI (62% vs. 37% without AKI; p n  = 244). Patients with AKI presented infections more often than without AKI (44% vs. 20%; p  Conclusions AKI was associated with incident in-hospital infections. However, newly occurring infections were not associated with an increased risk of mortality. Further studies are needed to understand how AKI affects distant organ function and associated clinical outcomes.