A process for preparing trisubstituted phenyl derivatives comprising a group (1H-1,2,4-triazol-1-yl) alkyl

2011 
A process for preparing a compound of formula II ** ** Formula wherein R1 and R2 are in position 3 and the position of the benzene ring of the compound of formula I ** ** Formula respectively and represent isopropyl substituted in the 2-position with cyano, and X is methylene, in which a compound of formula I ** ** formula wherein R1 and R2 and X are as defined above and Z is a leaving group, is reacted with 1, 2,4-triazole in a solvent which allows precipitation of a compound of formula III, wherein R1 and R2 and X are as defined above, wherein the compound of formula III is precipitated in the selected solvent and separates as a desired product not precipitate the reaction mixture.
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