Solitary Rectal Ulcer Syndrome

Solitary rectal ulcer syndrome (SRUS) is an uncommon benign disorder of the anterior wall of the rectum. It was first described by Cruveilhier in 1829, and subsequently it was presented as a clinical entity by Madigan and Morson in 1969. This condition is often associated with defecation disorders. The term “solitary rectal ulcer” is inadequate, since the ulceration may be multiple, not confined to the rectum, and the lesions may present as hyperemic mucosa or polypoid rather than ulcerated. Internal prolapse or intussusception most often precedes the endoscopic presentation. Excessive straining at defecation and spastic pelvic floor are associated with SRUS.