Malation vs. Aedes aegypti (Linnaeus) (Diptera: Culicidae) de diferentes regiones de Venezuela

En Venezuela, el malation ha sido ampliamente usado en forma continua en programas de control de aedes aegypti. Por tal motivo se realizo un estudio en mosquitos provenientes de zonas urbanas con alta casuistica de dengue de los estados: Amazonas, Aragua, Bolivar, Lara, Merida y Zulia, para determinar el status de susceptibilidad en este vector al malation, en comparacion con la cepa susceptible referencial, Rockefeller (Rock). Se hicieron bioensayos en botellas tratadas con el insecticida malation evaluando la dosis diagnostica 100ug/mL en 30 minutos y ensayos bioquimicos en microplacas para determinar mecanismos metabolicos asociados al status frente al insecticida. Los resultados de los bioensayos mostraron que existe susceptibilidad a malation, lo cual fue confirmado por pruebas bioquimicas. Sin embargo, se encontraron diferencias significativas entre todas las cepas evaluadas con valores de P In Venezuela, malathion has been widely used continuously in control programs for Aedes aegypti. Therefore, a study in mosquitoes from urban areas with high dengue casuistry in the states of Amazonas, Aragua, Bolivar, Lara, Merida and Zulia was conducted to determine the status of this vector susceptibility to malathion, compared with the reference susceptible strain, Rockefeller. Bioassays were done on bottles treated with the insecticide malathion, 100ug/mL evaluating the diagnostic doses in 30 minutes and biochemical assays in microplates were performed to determine metabolic mechanisms associated with status against insecticide. The bioassay results showed that there is malathion susceptibility, which was confirmed by biochemical tests. However, significant differences were found among all strains assessed values of P