Nuclear variations of quinuclidine substance P antagonists: 2-diphenylmethyl-1-azabicyclo[3.2.2]nonan-3-amines
1993
Abstract The synthesis and SAR of a series of 1-azabicyclo[3.2.2] analogues of the nonpeptide substance P antagonist CP-96,345 are described. The results demonstrate the sensitivity of the substance P receptor toward alterations in the nuclear structure of CP-96,345.
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