Co-regulation of the antagonistic RepoMan:Aurora-B pair in proliferating cells

Maria Giulia Manzione,Jan Rombouts,Mikhail Steklov,Lorenzo Pasquali,Anna Sablina,Lendert Gelens,Junbin Qian,Mathieu Bollen

Co-regulation of the antagonistic RepoMan:Aurora-B pair in proliferating cells

2020

Maria Giulia Manzione
Jan Rombouts
Mikhail Steklov
Lorenzo Pasquali
Anna Sablina
Lendert Gelens
Junbin Qian
Mathieu Bollen

Chromosome segregation during mitosis is antagonistically regulated by the Aurora-B kinase and RepoMan-associated phosphatases PP1/PP2A. Aurora B is overexpressed in many cancers but, surprisingly,...

Keywords:

Phosphatase
Chromosome segregation
Aurora B kinase
Protein phosphatase 2
Mitosis
Cell biology
Molecular biology
Biology
Kinase
Cell cycle
poor prognosis
Enzyme

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