128-channel laser optoacoustic imaging system (LOIS-128)for breast cancer diagnostics
2006
We have designed, fabricated and tested a new 128-channel laser optoacoustic imaging system (LOIS-128) for cancer
diagnostics consisting of an acoustic probe with 128 PVDF transducers, a digital signal processor with 128 independent
channels, and software for reconstruction of optoacoustic images. The system was capable of continuous planar imaging
(at rates up to 1 Hz) of small (less than 1 cm) tumors at depths over 6 cm. The directivity of the optoacoustic transducers
used in LOIS-128 assured that signal detection at all angles within a narrow imaging slice was at least 40% of the
maximal signal. The signal detection was better than 70% of the maximum for about 75% of the image in the image
slice and close to zero for signals coming from out of the image slice. LOIS-128 could image high-aspect-ratio objects
with about 0.5 mm resolution. Finally, with the designed image reconstruction algorithm we were able to estimate
absorption coefficients for test objects with accuracy of at least 5%.
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