Características clínicas y bioquímicas al momento del diagnóstico de hipotiroidismo en mujeres adultas

espanolEl hipotiroidismo es un sindrome clinico y bioquimico. Los objetivos del presente trabajo fueron describir y establecer las caracteristicas clinicas y bioquimicas mas prevalentes al momento del diagnostico de hipotiroidismo en mujeres adultas. Para ello se realizo un estudio descriptivo, retrospectivo y de corte transversal. Se seleccionaron 203 historias clinicas de mujeres con diagnostico de hipotiroidismo del Hospital Escuela de Agudos Dr. Ramon Madariaga, Posadas (Misiones). La caracteristica clinica mas prevalente fue la astenia y se presento en el 41% (n=83) de las pacientes. El 46% presento hipertrigliceridemia, 39% hipercolesterolemia, 38% glucemia en ayunas alterada, 17% hipertension, 23% sobrepeso y 52% obesidad. Las mujeres con hipotiroidismo clinico mostraron 5 veces mas riesgo de presentar trigliceridos elevados que las mujeres con hipotiroidismo subclinico (OR=5,2; IC 95%= 1,93-14,04). Todas presentaron al menos una caracteristica clinica o bioquimica, siendo las mas frecuentes, dentro de estas ultimas, la hipertrigliceridemia y la glucemia en ayunas alterada. EnglishHypothyroidism is a clinical and biochemical syndrome. The objectives of this study were to describe and establish the most prevalent clinical and biochemical characteristics at the time of the diagnosis of hypothyroidism in adult women. To do so, a descriptive, retrospective and cross-sectional study was carried out. Two hundred and three clinical histories of women diagnosed with hypothyroidism from the Hospital Escuela de Agudos Dr. Ramon Madariaga, Posadas (Misiones) were selected. The most prevalent clinical feature was asthenia and it was present in 41% (n = 83) of the patients. 46% presented hypertriglyceridemia, 39% hypercholesterolemia, 38% altered fasting glycaemia, 17% hypertension, 23% overweight and 52% obesity. Women with clinical hypothyroidism showed a 5 times higher risk of presenting high levels of triglycerides than women with subclinical hypothyroidism (OR = 5.2; 95% CI = 1.93-14.04). All women presented at least one clinical or biochemical characteristic, being the most frequent, within the latter, hypertriglyceridemia and altered fasting glycaemia.