Óxido nítrico inalatório no tratamento da hipertensão pulmonar persistente do recém-nascido

Objetivos: conhecer as indicacoes do uso de NOi, dose media utilizada e resposta ao tratamento em recem-nascidos internados em Unidade de Terapia Intensiva Neonatal. Metodos: foram analisados 62 prontuarios e considerados dois grupos de recem-nascidos (RN) de acordo com o desfecho para sobrevida (n=39) ou obito (n=23). Testes t-Student e binomial, p0,05). A dose inicial de NOi e a duracao do tratamento foram maiores nos RNs que sobreviveram (p0,05). O indice de oxigenacao foi significativamente mais alto nos obitos (p Objectives: To know the inhaled nitric oxide (iNO) use indications, the average used dose, and the reaction to treatment in newborns hospitalized at the Neonatal Intensive Care Unit. Methods: 62 medical records were analyzed and two newborn groups were considered according to the survival (n=39) or death (n=23) outcome. t-Student and binomial tests, p0.05). Congenital heart defect, pulmonary hipoplasia, sepsis, and hyaline membrane syndrome (HMS) were more frequent in newborns that evolved to death, while the meconium aspiration syndrome (MAS) was more present in the ones that survived (p0.05). The iNO initial dose and treatment time were superior in newborns that survived (p0.05).The oxygenation index was significantly higher in the deceased ones (p