Tandem - duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cel

5,6-Dihydro-prostacyclin (PGI1) analogs substituted with hydroxyphenyl groups, illustrated for example, by a compound of the formula i.e. 9-deoxy-6S,9 alpha -epoxy-17-(o-hydroxyphenyl)-18,19,20-trinor-PGF1, said products having pharmacological utility.