Proteomics of human pancreatic juice

Pancreatic juice has recently been characterized in detail using proteomic methods. The cataloging of proteins from healthy individuals and those diagnosed with pancreatic cancer has revealed the presence of a number of proteins in pancreatic juice that could serve as potential biomarkers for cancer. Because obtaining pancreatic juice is not trivial, it is possible that these biomarkers can be detected in serum using more sensitive methods like ELISA. Here, we discuss the protein constituents of pancreatic juice with special reference to cancer biomarkers.