High strength capsaicin cream for osteoarthritis pain: Rapid onset of action and improved efficacy with twice daily dosing

In a randomized, single-blind, 28-day study, a new high strength capsaicin cream (0.25%) applied twice daily (n = 31) was compared with four-times-daily application of low strength capsaicin cream (0.025%; n = 29) for the treatment of pain associated with osteoarthritis. High strength capsaicin prov