A Facile One-Pot Three-Component Synthesis of 5-（Trifl uoromethyl）-4,7-dihyd ro-[1,2,4]-triazolo[1,5-a] pyrimidine Derivatives in Ionic Liquid

An efficient one-pot synthesis of 5-（trifluoromethyl）-4,7-dihydro-7-aryl-[1,2,4]triazolo[1,5-a]pyrimidine derivatives was performed via the reaction of aryl aldehyde, 3-amino-l,2,4-triazole and ethyl 4,4,4-trifluoro-3- oxobutanoate or 4,4,4-trifluoro-l-phenylbutane-1,3-dione in ionic liquid. This method has the advantages of short synthetic route, operational simplicities, mild reaction conditions, high yields and eco-friendliness.