Chronic neurological disease as a independent risk factor for death in severe covid-19 cases

COVID-19 is a multisystemic disease with a wild severity range, being some chronic diseases risk factors for unfa-vorable evolution. It has been suggested are chronic neurological diseases are associated to higher mortality in COVID-19 patients;such association however, has not been described enough. In this context, this study seeks to evaluate whether the presence of previous chronic neurological disease is a factor associated with higher mortality in hospitalized severe cases of COVID-19. For this, the association between those variables was investigated in 87,871 patients through univariate (risk ratio and χ2 test) and multivariate (Poisson regression) analysis. It was found that the mortality rate for patients presenting chronic neurological disease was 23% higher (),this being an independent and statistically significant association (RR = 1.23, 95% CI = 1.2-1.3;p-value < 0.001). Therefore, more studies are needed to better characterize this association.